Ronny Knol, Emma Brouwer, Frans J. C. M. Klumper, Thomas van den Akker, Philip DeKoninck, G. J. Hutten, Enrico Lopriore, Anton H. van Kaam, Graeme R. Polglase, Irwin K. M. Reiss, Stuart B. Hooper and Arjan B. te Pas
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Most preterm infants fail to aerate their immature lungs at birth and need respiratory support for cardiopulmonary stabilization. Cord clamping before lung aeration compromises cardiovascular function. Delaying cord clamping until the lung has aerated may be beneficial for preterm infants by optimizing hemodynamic transition and placental transfusion. A new purpose-built resuscitation table (the Concord) has been designed making it possible to keep the cord intact after preterm birth until the lung is aerated and the infant is respiratory stable and breathing [Physiological-Based Cord Clamping (PBCC)]. The aim of this study is to test the hypothesis whether stabilizing preterm infants by PBCC is at least as effective as the standard approach using time-based Delayed Cord Clamping (DCC).